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Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues

From school age (8-10 hours a night) to older adult (7-8 hours a night) there is a slow but gradual reduction in required sleep

Targeted therapy remains a key strategy in treating hematological malignancies

Indeed, increased GLP-1 levels are associated with higher resting energy expenditure and enhanced fat oxidation rates in humans (38)

Acknowledgements All the authors would like to thank the Ensembl platform ( the Cytoscape platform ( and Mingjie Chen (Shanghai NewCore Biotechnology Co., Ltd.) for providing free data analysis and visualization tools ( Ming-Rui Li would like to thank the biliili platform and the fellow netizens ( for their kind help with R coding