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This method ensures that the body adjusts to the medication, maximizing its efficacy while minimizing potential side effects

They were interested in whether there were subgroups of patients that may be at risk, with the goal of identifying them so that clinicians could have a better idea of who they should monitor more closely

2025: Novo Nordisk announced positive Phase 3 ESSENCE trial results for semaglutide in early Alzheimer's disease, reporting statistically significant slowing of cognitive and functional decline a breakthrough data package that could establish GLP-1 therapy as a neuroprotective agent and open an addressable market of 6.5 million Alzheimer's patients in the U.S

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doi: 10.1056/NEJMoa1411892, [DOI] [PubMed] [Google Scholar] Plamboeck A., Veedfald S., Deacon C