semaglutide compounding news november 2025 September 15, 2025: Telehealth company must stop implying its compounded GLP-1 is FDA-approved, warns FDA – Partnership for Safe Medicines Compounded "semaglutide" is not FDA-approved

But its still patchy

--- What You Need Before You Start Before reconstituting: Retatrutide vial (common sizes: 10mg, 20mg) Bacteriostatic water (BAC water) not saline, not plain sterile water Insulin syringes: 2931g, 1/2" needle, 100-unit markings Alcohol swabs Sharps container BAC water is the only correct diluent

It remains in Phase 3 clinical trials through the TRIUMPH program, which includes multiple studies examining different patient populations and endpoints

Some weeks show small gains despite adherence

This variation shows how individual sensitivity to incretin and glucagon signalling can set practical limits on the maximum dosage a person can endure, even in a tightly controlled research setting