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Why Glutathione for Skin Brightening
Once oxidized by lipoxygenases (LOXs), these products can generate lipid peroxides like polyunsaturated fatty acid hydroperoxide (PUFA-OOH) (Figure 1) ( 2.4 Imbalance of antioxidant system Excessive ROS production and weakened antioxidant defenses together lead to increased oxidative stress, which is mechanistically associated with the progression of PF (von Krusenstiern et al., 2023)
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Mol Pharmacol 84:190200
Notably, glutaminolysis inhibitors (compound 968) can prevent ischemia/reperfusion-induced cardiac damage [86]
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