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Joos GF, De Swert KO, Pauwels RA

35 While the legal landscape of 8-THC is constantly changing, it is currently available for sale in 23 states in the U.S

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Acta Pharm Pharm Sci

Direct Adrenergic Agonism: Ephedrine is also able to directly bind to multiple post-synaptic adrenergic receptor subtypes to initiate intracellular signaling cascades: : Activation of vascular smooth muscle 1 -Adrenergic Activation 1 -adrenergic receptors produces arterial and venous vasoconstriction, leading to an increase in systemic vascular resistance (SVR), diastolic blood pressure, and systolic blood pressure (Solanki et al, 2014)