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A healthcare professional can assess whether dose adjustment of the medication is appropriate, review concurrent medications that may contribute to constipation, and exclude other underlying causes

Dual GIP/GLP-1 receptor agonists, such as Zepbound, combine the effects of GIP and GLP-1 receptor activation to better control blood sugar levels

At the highest retatrutide dose, about 1 in 5 participants experienced it

The research rationale for combining the two peptides rests on their convergent yet mechanistically separate modes of action

For a comprehensive understanding of side effects management, the GLP-1 fatigue guide , GLP-1 headache guide , and hair loss guide cover specific concerns in detail