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Beyond Diabetes: Semaglutide's Role in Modulating Mood Disorders through Neuroinflammation Pathways

GLP-1 receptor agonism is the mechanism semaglutide uses alone

A 2024 randomised trial in adults with elevated fracture risk found that semaglutide reduced hip bone mineral density by 2.6% and lumbar spine density by 2.1% at 52 weeks compared with placebo

Clinical trials spanning 23 years show semaglutide is safe and maintains effectiveness without tolerance buildup

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