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10 Las guas de prctica clnica AACE/ACE 2017 no se oponen a la combinacin de un AGLP-1 y iSGLT2 como tratamiento doble o triple 9 y en la actualizacin de la Asociacin Americana de Diabetes (ADA) y la Asociacin Europea para el Estudio de la Diabetes (EASD) de 2017 no pudo hacerse una recomendacin basada en evidencia para la administracin de esta combinacin debido a la falta de datos disponibles que apoyan esta prctica