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Although cardiovascular safety was established with GLP-1 receptor agonists, the findings suggest that stroke-related benefits may vary across different GLP-1 receptor agonists

In addition to Pentelute and Zhang, other researchers listed as authors on the preprint are postdoc Sebastian Pomplun, grad student Alexander Loftis, and research scientist Andrei Loas.

Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial

REDUCED PAIN AND INFLAMMATION This compound works by not only promoting the healing of injured muscles but also reducing pain and inflammation from rigorous activity

They identified the upregulation of AMTN and DKK2, and the downregulation of MSLN, highlighting their critical roles in OA-related pathological mineralization and bone remodeling