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Anyone handling retatrutide in Canada should read that advisory directly and understand it applies to them

The FDA expanded semaglutide's (Wegovy) use to reduce the risk of cardiovascular death, heart attack, or stroke in adults with cardiovascular disease and overweight or obesity, based on a cardiovascular outcomes trial in which it reduced major adverse cardiovascular events by 20% compared with placebo

P., Bartchewsky, W

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However, additive effects on appetite suppression and nausea are possible when both medications reduce hunger simultaneously