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Dosing by Route Protocol Timeline Weeks 12 (ramp): 200250 mcg once daily subcutaneous

In medial collateral ligament (MCL) injury models, BPC-157 administered intraperitoneally (10 g or 10 ng/kg once daily), topically as a cream layer, or orally in drinking water consistently produced functional, biomechanical, macroscopic, and histological healing improvements throughout the 90-day study period

Such biomarkers could help identify patients most likely to respond to treatment and could facilitate personalized treatment approaches

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These trials included both single-dose pharmacokinetic studies and long-term efficacy trials extending up to 24 weeks of continuous administration