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Witzel S, Maier A, Steinbach R, Grosskreutz J, Koch JC, Sarikidi A, et al

Others, including most of those under FDA review in July, are unapproved compounds that have nonetheless amassed a cult following among so-called looksmaxxers, bodybuilders, wellness influencers, and Silicon Valley biohackers

Wearing sunscreen and sun-protective clothing and avoiding the sun as much as possible can help prevent hyperpigmentation

Each of the three pathways contributes different effects: GI Side Effects (Primarily from GLP-1) The GLP-1 component is responsible for most gastrointestinal side effects because it slows gastric emptying and affects gut motility: Metabolic Effects (From Glucagon Component) The glucagon component may cause slight increases in: Heart rate: Average increase of 5-10 bpm due to increased metabolic rate (similar to tirzepatide) Body temperature: Some users report feeling warmer, especially after meals (thermogenesis) Energy levels: Variable

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