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This complexity makes identifying and specifically targeting the most relevant pathways within this vast network difficult, as targeting a single oxidant or source may be insufficient and could potentially interfere with physiological redox signaling, given ROSs crucial dual roles as signaling molecules (as elaborated in Section 2.2) (Liu L

These mechanisms work synergistically to reduce atherosclerosis, a proinflammatory process that drives the progression of cardiovascular diseases, such as coronary heart disease, peripheral vascular disease, and stroke

Linagliptin added to sulphonylurea in uncontrolled type 2 diabetes patients with moderate-to-severe renal impairment