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Another critical component, alternative oxidase (AOX), attenuates mitochondrial ROS generation by providing an alternative electron transport route within the respiratory chain

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They compare patients initiating treatment in a given month to those who initiate 12 months later in a one-year follow-up design and 60 months later in a five-year follow-up design, allowing them to control for underlying time trends and baseline health differences

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Measurable collagen remodeling from consistent light therapy generally requires 412 weeks of regular sessions