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In the central nervous system (CNS), during embryogenesis and adulthood, efferocytosis by ramified microglia balances cell death and neurogenesis, ultimately supporting brain development, optimizing neuronal connectivity, and ensuring that inflammatory responses remain appropriate and effective [25, 26]

Conclusion Our systematic review provided suggestive evidence that Nrf2 activators have a potentially beneficial role in improving autism-like behaviors and abnormal molecular alterations through oxidant stress, inflammation, and mitochondrial dysfunction

It is also studied for effects on inflammation balance and oxidative stress, which can influence how skin looks and feels over time

What evidence supports remaining at 2.5 mg of tirzepatide before dose escalation