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Medications that may be considered are estradiol (patch, insert, or gel), micronized progesterone, and thyroid replacement if necessary

if nighttime cravings dominate, evening dosing makes more sense

Additionally, advanced cirrhosis patients often experience abdominal symptoms such as pain and reflux, and are sarcopenic, a factor independently associated with mortality (13)

*Correspondence: Cyriac Abby Philips, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

3 Exercise has also been found to improve overall well-being, physical function, reports of pain, tenderness, and muscle strength