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Gastric Distension Induces C-Fos in Medullary GLP-1/2-Containing Neurons. American Journal of Physiology
(PubMed) Hadamitzky M, Distler R, Meyer T, et al
Statistical analysis The statistical significance between multiple data sets was determined by one-way ANOVA
Key gaps No semaglutide trial programme publicly reports validated vaginal symptom patient-reported outcomes (dryness scales, dyspareunia scores, pH/microbiome endpoints) in regulatory product information, limiting incidence estimation for vaginal endpoints
The benefits of these drugs likely extend beyond their current use in the treatment of diabetes and obesity to improve glycaemic control, as cardiovascular benefits have been observed across diabetic and pre-diabetic populations
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