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Ke Wang, Department of Infectious Disease, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Drink Water All Day: Aim for 6480 oz

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Malate is the perfect complement to citrulline as Prez-Guisado et al points out Malateis capable of behaving as a metabolic shuttle between cytoplasm and mitochondria, enables bypassing of blockade of the oxidative pathway induced by ammonia, and hence limits accumulation of lactic acid by reorienting it toward pyruvate genesis and its aerobic utilization or neoglucogenesis

Metabolic flexibility in response to a variety of stimuli, including dietary changes, is an important feature of muscle energetics