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can be given with or without meals at any time of the day

In some embodiments, the otic formulation or composition comprises between about 0.001% to about 5% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Unlike full-length hGH, AOD-9604 does not bind the growth hormone receptor and has shown no measurable effect on IGF-1 levels, glucose homeostasis, or somatic growth in the published preclinical literature

Szasz A

Disorders of androgen receptor sensitivity or enzymatic defects in T synthesis may also manifest during this phase (normal/elevated testosterone levels associated with relatively elevated gonadotropins in androgen receptor defects, reduced T levels with variable gonadotropins in enzymatic defects of gonadal steroidogenesis)