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In a randomized, double-blind, placebo-controlled study, 93 subjects with colorectal polyps and 86 healthy subjects were given a placebo, folic acid (400 or 1,200 g/day), or folic acid (400 g/day) plus riboflavin (5 mg/day) for 45 days

This finding suggests that IFNG functions as an endogenous inhibitor of SLC7A11, enhancing our understanding of the interplay between the immune response and ferroptosis in the context of cancer [209]