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Lamkanfi M, Sarkar A, Vande Walle L, Vitari AC, Amer AO, Wewers MD, et al

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"Incretin mimetics as a novel therapeutic option for hepatic steatosis"

15,62 The Gly4D-Ala derivative of exendin-4 had similar potency to exendin-4 itself in inducing conformational changes in the heterotrimeric G protein, albeit with modestly lower maximal response, while the Gly4( S,S )-ACPC derivative of exendin-4 was markedly less potent (Fig