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Aging Cell 14 , 644658 (2015)

Protein adequacy : Collagen synthesis depends on adequate protein, vitamin C, copper, zinc, and specific amino acids like glycine and proline

Clinical Relevance: These findings explain GHK-Cu's accelerated wound closure observed in clinical settings and its interest as a therapeutic candidate for chronic wounds, post-surgical recovery, and tissue regeneration applications

Because GHK-Cu arrives as lyophilized powder reconstituted to a researcher-chosen concentration, the same target dose corresponds to different syringe volumes depending on the reconstitution choice