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The bigger picture A January 2026 retrospective cohort study published in The Lancet , conducted at Mayo Clinic, followed 120 postmenopausal women on tirzepatide for at least 12 months

The findings of the study also demonstrated that the majority of patients (97.5%) exposed to GLP-1 RAs used semaglutide, while the remaining 2.5% of patients used lixisenatide

Aroor AR, Sowers JR, Jia G, DeMarco VG: Pleiotropic Effects of the Dipeptidylpeptidase-4 Inhibitors on the Cardiovascular System

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Since glutathione levels naturally decrease with age, maintaining optimal levels can help defend against age-related diseases while supporting skin firmness, elasticity, and a youthful appearance