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Rats were acclimated for five days and randomly assigned to their respective treatment groups, housed in polycarbonate (PC) cages (identified with dates, number of study, group, dose, number and sex of each animal) at 2024 C, with a relative humidity of 4070% and noise level of 60 dB, illumination 12 h per day (fluorescent lighting), a standard good laboratory practice (GLP) diet and fresh water ad libitum

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PMID 18701638

The peptide's actin-sequestering activity proves particularly important for endothelial cell migration, with studies showing TB-500 significantly enhances endothelial cell migration rates and tube formation in angiogenesis assays while promoting the formation of stable, mature blood vessels with appropriate pericyte coverage