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36, 37, 38, 39, 40, 41, 42, 43, 44, 45 This is partly because some studies were performed in a small sample size, and further confirmation is needed

Br J Clin Pharmacol 1995;40:7982

By deacetylating a variety of key proteins, SIRT1 enhances the antioxidant capacity of cells, reduces the production of ROS, and inhibits lipid peroxidation, thus alleviating the damage caused by ferroptosis to nerve cells (Xie et al., 2022

Bonus: In addition to supporting muscle maintenance, creatine has neuroprotective effects, may support mood, and can improve cognitive performancea win for total wellness

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