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sulfonylureas and insulin may require dose reduction to prevent hypoglycemia when initiating a potent incretin-based agent Discuss realistic titration timelines: patients should understand that therapeutic weight loss at the target dose takes 12 to 20 weeks to become fully apparent Monitoring During Therapy Recheck HbA1c and fasting glucose at 8 and 16 weeks during titration if the patient has type 2 diabetes, as insulin or sulfonylurea doses may need downward adjustment

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For some, green tea and coffee is the perfect way to combat fatigue

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