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For decades, the US has been the undisputed leader in science and technology R&D, fuelling a pipeline that delivered many of the worlds breakthrough medicines (Figure 2)

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More serious but less common side effects to watch for at this dose include acute pancreatitis (symptoms: severe abdominal pain radiating to the back, nausea, vomiting), gallbladder problems (symptoms: sudden pain in the upper right abdomen, fever, jaundice), and significant hypoglycemia if combined with certain diabetes medications