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Side effect profile Both formats produce similar GLP-1-related side effects because they deliver the same active molecule
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The PAR2-activating coagulation protease FXa ( F10 ), known to be expressed in various extrahepatic cell types, had low mRNA expression in the intestinal crypt cells at our sequencing depth, but a survey of recently published single-cell gene expression data showed that F10 was expressed in proximal enterocytes, whereas Tmprss2 and F2rl1 predominantly colocalized in the early enterocytes (36)
As a result, cost-related issues are slowing the markets growth despite strong clinical demand and efficacy
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