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That changed after chemist Bruce Merrifield developed solid-phase peptide synthesis, a breakthrough that earned him the Nobel Prize in 1984 and dramatically simplified production of these fragile biomolecules by allowing them to be built much more efficiently compared to purification
dermatology 37, 311315
Three or four cycles between room temperature and refrigerator cause cumulative damage that compounds with each cycle
It defends against exogenous and endogenous stressors, prevents loss of water and nutrients, and maintains skin homeostasis (Passeron et al., 2021)
Burks, A
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