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Known Vision-Related Risks Associated with GLP-1 Drugs Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) One of the most serious vision-related side effects linked to Ozempic, Wegovy, and similar GLP-1 drugs is NAION, a condition sometimes referred to as an eye stroke. NAION occurs when there is a sudden decrease or blockage of blood flow to the optic nerve, resulting in damage that prevents visual signals from reaching the brain