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Therapeutic Angiogenesis for Treating Cardiovascular Diseases

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They postulated an anti-inflammatory mechanism, quoting previous similar findings in animal trials [97, 98], by directly inhibiting TNF- induced NF-B resulting in reduction of proinflammatory markers, including IL-6, and also reducing nitric oxide species and reactive oxygen species while reversing eosinophilic infiltration into the lung tissues

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FABAD Journal of Pharmaceutical Sciences, 32 , 7989

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That potential places MOTS-c at the frontier of a profoundly important clinical question: how to maintain the metabolic benefits of exercise in bodies that can no longer perform it [2]

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