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This binding activates adenylate cyclase, leading to elevation of cAMP and PKA, which finally enhances insulin biosynthesis and secretion, and suppressed glucagon secretion [4]

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Even though clinical trials have shown some positive results on motor function in patients with Parkinson's disease treated with exenatide (73), a recent Cochrane review found 'low-certainty evidence that exenatide improves motor impairment' in patients with Parkinsons disease (74)

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