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This discovery was not only of significant clinical importance for Parkinson disease drug treatment but also provided new perspectives for understanding how gut microbiota influences host catecholamine metabolism

The confirmation of prednisone or cortisone intake was based on the answer to the question of Have you ever taken any prednisone or cortisone pills nearly every day for a month or longer?, and those who answered yes were recorded as positive [19]

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This exact pattern has generated hundreds of poison control calls and FDA adverse event reports