The gold standard treatment for lymphedema is called Complete Decongestive Therapy, or CDT
Because it leaves your body so slowly, a single weekly injection builds up to and maintains a steady level in your system
This lifts the subcutaneous tissue away from the muscle and any deeper veins, creating a safe zone for the needle
Cyclisation in Melanotan II flattens that profile, giving comparable potency at MC1R and MC4R and only modestly less at MC3R and MC5R, which is why Melanotan II is used as the non-selective positive control while Melanotan 1 is used where an MC1R-weighted reference agonist is wanted
There is some indication that GHK might interfere with mechanisms of oxidative stress and inflammation, such as iron release from ferritin, a protein complex involved in storing iron, thereby potentially mitigating lipid peroxidation