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The known risks associated with these medicines are reflected in their FDA-approved product labeling which, collectively, FDA has reviewed more than 40 times and are discussed in textbooks, treatment guidelines and journals. Novo Nordisk updates product labels in cooperation with the FDA and consistent with federal regulations to reflect the most current understanding of the safety and efficacy profile of our medicines, said Flavia Brakling, a spokesperson for the company

This regulatory mechanism may stem from its detergent-like effect, which affects the structure and function of the cell membrane [122]