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The article suggests evidence-based GLP-1 therapy may be appropriate for people who have struggled with weight loss despite diet and exercise, or who have type 2 diabetes or cardiovascular risk factors

Gut 55 (3), 327333

While GLP-1 aids in appetite control, healthy eating habits are crucial

(5) As these agents become increasingly integrated into clinical practice, their effects on weight, metabolic regulation, and systemic inflammation carry important implications for orthopedic surgery