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Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice

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Glutathione plays a significant role in maintaining the redox (reduction-oxidation) balance in cells, but GSNO and GSSG each have unique characteristics: S-Nitroso-L-glutathione (GSNO): GSNO is a nitric oxide (NO) donor in cells, and it is part of the group of S-nitrosothiols