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Kadowaki T, Chin R, Ozeki A, et al

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[3] Other common adverse effects reported during the clinical trials include back pain, upper respiratory tract infections, melanocyte naevus, decreased appetite, migraine, dizziness, weakness, fatigue, lethargy, sleepiness, hot flashes, abdominal pain, diarrhea, vomiting, flushing, development of warts, spots, and freckles, and itchy skin (between 1% and 10% of people)

Signs concentration may be too high Persistent irritation that doesn't resolve after two weeks of consistent use signals concentration exceeding your skin's tolerance

This helps rebuild your skins matrix, making it smoother and more resilient