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Following the emergence of MDM2 as a p53 inhibitor, pharmacological disruption of the interaction between these two proteins has been explored to reactivate p53 in human tumors that express wild-type TP53
Selenium, cadmium (Cd), arsenic (As), and lead (Pb) in particular have attracted a lot of study due to their complex relationships with thyroid function and trace elements [3]
Proteomic data derived from three independent biological replicates are presented as mean s.d
Regular use has also been linked to a higher likelihood of asthma, infertility, and hearing loss (especially in men under 50)
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