Considering the potential of secondary bile acids to increase L-cells and GLP-1 secretion by TGR5, TGR5 agonists are promising drug candidates for increasing L-cells and GLP-1 secretion [180, 181]
The unexpected finding that exendin-4 has neuroprotective effects in animal models of various neurodegenerative diseases opens the door to testing this drug as a treatment for a number of devastating human diseases, such as Alzheimers. I think the fact that we have been able to take this substance found in nature and consider applying it in such incredibly diverse waysto treat diabetes, to possibly treat neurological diseaseadds to the growing body of support for a link between the endocrine and nervous systems, adds Dr
Chen J, Xie JJ, Shi KS, et al
Thanks to its low self-pay prices, the Wegovy pill also tends to cost less than many other GLP-1s, including Zepbound and Saxenda
People are starting to embrace this burgeoning GLP-1 era, but with so many supplements on the market, choosing the right one for you can feel overwhelming
