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Clinical Trial Efficacy Data The approval is backed by two pivotal Phase 3 trials within the CORALreef clinical program evaluated at week 24: CORALreef Lipids Trial: Achieved a statistically significant 56% placebo-adjusted reduction in LDL-C (with a post-hoc analysis showing a 60% reduction when biological inconsistencies were removed)

Most providers require an online health assessment and physician review before prescribing treatment if medically appropriate

Persistent or expanding bruising, particularly if accompanied by pain or firmness, should prompt medical evaluation to rule out hematoma formation

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Consult with your healthcare provider to understand what you can expect in your unique situation. How long does it take semaglutide to start working for weight loss