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The compound functions as a dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor, two signaling systems that play central roles in endocrine regulation of metabolism

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The relative fluorescence units (RFU) from each sample were normalized based on (1) hybridization controls on each microarray to correct for systematic variability in hybridization and (2) median signal based on all features for each dilution to correct for variability across plates according to the SomaScan Data Standardization guidelines (SomaScan Data Standardization and File Specification Technical Note (SSM-020))