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Month 3 Summary: The Transformation Begins Weight loss: 4-8 pounds this month (15-19 pounds total, 7-9% of starting weight) Side effects: Dramatically improved from month 2 Energy: Normalized to near-baseline levels Discontinuation rate: Only 2-3% stop during month 3 (completion probability high) Psychological state: Confident, encouraged, sustainable feeling Key achievement: Completed dose escalation successfully

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The molecular mechanisms of incretin resistance in Type 2 Diabetes Mellitus (T2DM)