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To determine whether dysregulated hepatic glutathione homeostasis and TNF can synergistically contribute to hepatocyte death, we performed cell culture studies using both human hepatoma cells and mouse non-transformed hepatocytes

Exenatide products (Byetta, Bydureon) have been discontinued in the US market

Glutathione interventions are not appropriate for all individuals

Results: Age, gender, history of gastrointestinal disorders, and number of combined oral medications were found as risk factors for the occurrence of GISEs in patients with T2DM using GLP-1RAs ( p 0.05 for the validation set)

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