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These observations are strictly preclinical and are used to explore how circadian gene regulation intersects with tumor biology and treatment-response research

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A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

in vivo stability, and limited blood-brain barrier permeability ( 2.3 Lipid peroxide accumulation Polyunsaturated fatty acids (PUFAs), which are major constituents of organelle membrane phospholipids, are particularly prone to peroxidation during ferroptosis (Poindessous et al., 2024)

Dual regulation of cytosolic ascorbate peroxidase (APX) by tyrosine nitration and S-nitrosylation