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Peptides RRDY and RL identified from yam diosgenin were used in oral glucose tolerance test (OGTT) on normal ICR mice, and peptide RRDY reduced DPP-IV activity controlling blood glucose levels in normal mice (77)

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Nonetheless, our study demonstrates that a persistent imbalance between oxidative stress toxicity and reduced ANTIOX is a key component of Long COVID and that increased aldehyde, neutrophil-associated MPO, protein carbonyl, and NO production are the major neurotoxic pathways, which, when combined with decreased ANTIOX, may have a variety of detrimental effects as reviewed before [81]

2019;7: e14286