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Komi DEA, Mortaz E, Amani S, Tiotiu A, Folkerts G, Adcock IM (2020) The role of mast cells in IgE-independent lung diseases
This augmented height can lead to the production of pro-inflammatory cytokines such as IFN-, which promotes B cell class switching and initiates pathogenic autoantibodies production such as Immunoglobulin G (IgG) antibodies, most notably anti-dsDNA antibodies, typical lupus-characteristic markers, that induce additional inflammation and tissue damage (115, 118)
Enhanced Lipolysis and Fat Oxidation : Preclinical studies have shown that AOD-9604 increases the rate of lipolysis the natural process of triglyceride breakdownwhile simultaneously inhibiting new fat formation in adipose tissue
It has resulted in the proposal of the Glutathione Deficiency Hypothesis , which suggests that glutathione deficiency is a primary cause of biological aging