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Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

95% CI, 0.32 to 0.60) suicidal ideation compared to non-GLP-1 RAs anti-obesity treatments [80]

Most providers recommend discontinuing use at least 12 months before attempting pregnancy

In Type 2 diabetes, GLP-1 agonists help manage blood sugar by triggering the pancreas to release more insulin

Studies suggest that people who lose weight quickly, particularly with the aid of medications like GLP-1 receptor agonists, may have a higher likelihood of developing gallstones, which can cause severe abdominal pain and may require surgical intervention