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Encourage diet sources of B where possible, and adherence to the injection schedule.

Huan Huan Liu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Precision medicine approaches may also provide an opportunity to select patients who are receptive to the greater efficacy of this combination therapy

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