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Description

Trichostatin A (HDACi, 20 nM) was found to inhibit the maturation of dendritic cells by down-regulating the NF-B signaling pathway, thereby decreasing their ability to stimulate T cells (48)

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In mammals, four isozymes are expressed: PK-M1 is expressed in skeletal muscle, heart, and brain

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Voiculescu S, Zygouropoulos N, Zahiu C, Zagrean A

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